产品
编 号：F036637
分子式：C42H68N6O6S
分子量：785.09
分子式：C42H68N6O6S
分子量：785.09
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 110417-88-4
产品详情
生物活性：
Dolastatin 10 (DLS 10) is a potent antimitotic peptide that inhibits tubulin polymerization.
体外研究：
Dolastatin 10 is a unique pentapeptide that isolated from the sea hare Dolabella auricularia. These in vitro data are quite comparable to those of Dolastatin 10 and Auristatin PE, each of which has GI50 values of 10?5-10?6 μg/mL (10?2-10?3 nM) against a similar minipanel of human cell lines. The antibody-drug conjugate (ADC) comprises the anti-CD30 monoclonal antibody cAC10 conjugated to the cytotoxic agent monomethyl auristatin E (MMAE), a synthetic analog of the tubulin polymerization inhibitor Dolastatin 10.
Dolastatin 10 (DLS 10) is a potent antimitotic peptide that inhibits tubulin polymerization.
体外研究：
Dolastatin 10 is a unique pentapeptide that isolated from the sea hare Dolabella auricularia. These in vitro data are quite comparable to those of Dolastatin 10 and Auristatin PE, each of which has GI50 values of 10?5-10?6 μg/mL (10?2-10?3 nM) against a similar minipanel of human cell lines. The antibody-drug conjugate (ADC) comprises the anti-CD30 monoclonal antibody cAC10 conjugated to the cytotoxic agent monomethyl auristatin E (MMAE), a synthetic analog of the tubulin polymerization inhibitor Dolastatin 10.
产品资料
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