产品
编 号：F313690
分子式：C11H10BrN3
分子量：264.12
分子式：C11H10BrN3
分子量：264.12
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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50mg
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100mg
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200mg
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结构图
CAS No: 307538-42-7
产品详情
生物活性：
SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.
体内研究：
SMER28 (15-65 mg/kg; i.h.; daily, two days before irradiation and during the three days of irradiation) significantly protects against post-irradiation weight loss and enhances survival of mice at 65 mg/kg.Animal Model:14 to 16 weeks male mice (Balb/c)
Dosage:15, 65 mg/kg
Administration:Subcutaneous injection; two days before irradiation and during the three days of irradiation (total 5 days)
Result:Significantly protected against post-irradiation weight loss and enhanced survival of mice at 65 mg/kg.
体外研究：
SMER28 (5-200 μM; 24 hours) shows a dose dependent decline of cell viability.
SMER28 is a positive regulator of autophagy acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.
体内研究：
SMER28 (15-65 mg/kg; i.h.; daily, two days before irradiation and during the three days of irradiation) significantly protects against post-irradiation weight loss and enhances survival of mice at 65 mg/kg.Animal Model:14 to 16 weeks male mice (Balb/c)
Dosage:15, 65 mg/kg
Administration:Subcutaneous injection; two days before irradiation and during the three days of irradiation (total 5 days)
Result:Significantly protected against post-irradiation weight loss and enhanced survival of mice at 65 mg/kg.
体外研究：
SMER28 (5-200 μM; 24 hours) shows a dose dependent decline of cell viability.
产品资料
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