产品
编 号:F313052
分子式:C44H63N3O4
分子量:697.99
产品类型
结构图
CAS No: 306387-90-6
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产品详情
生物活性:
KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist.
体外研究:
KAAD-Cyclopamine inhibits pathway activation induced by 1 μM purmorphamine with an IC50 of 3 nM, wheras this cyclopamine derivative has an IC50 of 100 nM in Shh-LIGHT2 cells stimulated with 10 μM purmorphamine.