产品
编 号：F312348
分子式：C9H14Br2N2O
分子量：326.03
分子式：C9H14Br2N2O
分子量：326.03
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CAS No: 304-47-2
产品详情
生物活性：
Kynuramine dihydrobromide, an endogenously occurring amine, is a fluorescent substrate of plasma amine oxidase.
体内研究：
Kynuramine dihydrobromide (0.064-8 μg；脑室内；单剂量) 促进雌激素激发的去卵巢大鼠前凸行为。Kynuramine dihydrobromide (1.25-5.0 mg/kg；静脉注射；单剂量) 可增加大鼠的心率和血压。Animal Model:Female rats.
Dosage:0.064, 0.32, 1.6 or 8 μg.
Administration:Intraventricular injection; single does.
Result:Produced facilitation of lordosis behavior.
Animal Model:Male rats (about 200g).
Dosage:1.25, 2.5 and 5.0 mg/kg.
Administration:Intravenous injection; single does.
Result:Promoted heart rate and blood pressure.
体外研究：
Kynuramine dihydrobromide 在体外抑制突触前和突触后 α-肾上腺素受体。Kynuramine dihydrobromide 已被证明是狗脑动脉血清素受体的部分激动剂。Kynuramine dihydrobromide (20 μg/mL) 导致回肠轻微收缩，但未能改变胆碱能刺激的抽搐反应。
Kynuramine dihydrobromide, an endogenously occurring amine, is a fluorescent substrate of plasma amine oxidase.
体内研究：
Kynuramine dihydrobromide (0.064-8 μg；脑室内；单剂量) 促进雌激素激发的去卵巢大鼠前凸行为。Kynuramine dihydrobromide (1.25-5.0 mg/kg；静脉注射；单剂量) 可增加大鼠的心率和血压。Animal Model:Female rats.
Dosage:0.064, 0.32, 1.6 or 8 μg.
Administration:Intraventricular injection; single does.
Result:Produced facilitation of lordosis behavior.
Animal Model:Male rats (about 200g).
Dosage:1.25, 2.5 and 5.0 mg/kg.
Administration:Intravenous injection; single does.
Result:Promoted heart rate and blood pressure.
体外研究：
Kynuramine dihydrobromide 在体外抑制突触前和突触后 α-肾上腺素受体。Kynuramine dihydrobromide 已被证明是狗脑动脉血清素受体的部分激动剂。Kynuramine dihydrobromide (20 μg/mL) 导致回肠轻微收缩，但未能改变胆碱能刺激的抽搐反应。
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