产品
编 号：F311884
分子式：C18H23ClN2
分子量：302.84
分子式：C18H23ClN2
分子量：302.84
产品类型
规格
价格
是否有货
结构图
CAS No: 303-25-3
产品详情
生物活性：
Cyclizine hydrochloride, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine hydrochloride can be used for the research of nausea, vomiting, and dizziness.
体内研究：
Cyclizine (1-10 mg/kg) hydrochloride enhances locomotor activity of mice in a dose-dependent manner.
体外研究：
Cyclizine (100 μM) hydrochloride significantly inhibits nitrite accumulation and iNOS protein levels in the LPS-stimulated in RAW 264.7 cells supernatants.Cyclizine hydrochloride inhibits anti-IgE-induced histamine release from isolated human lung fragments, with an IC50 of 5.42 μM.
Cyclizine hydrochloride, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine hydrochloride can be used for the research of nausea, vomiting, and dizziness.
体内研究：
Cyclizine (1-10 mg/kg) hydrochloride enhances locomotor activity of mice in a dose-dependent manner.
体外研究：
Cyclizine (100 μM) hydrochloride significantly inhibits nitrite accumulation and iNOS protein levels in the LPS-stimulated in RAW 264.7 cells supernatants.Cyclizine hydrochloride inhibits anti-IgE-induced histamine release from isolated human lung fragments, with an IC50 of 5.42 μM.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备