产品
编 号：F311460
分子式：C22H23N3O
分子量：345.44
分子式：C22H23N3O
分子量：345.44
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
50mg
询价
询价
结构图
CAS No: 302799-86-6
产品详情
生物活性：
TCS 46b (Compound 46b) is a potent, selective and orally active NMDA NR1A/2B receptor antagonist with an IC50 of 5.3 nM. TCS 46b is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
TCS 46b (Compound 46b; 10 and 30 mg/kg; p.o. or i.p.; once) 在 6-OHDA 损伤大鼠中增强左旋多巴的作用。Animal Model:Sprague?Dawley rats, 6-hydroxydopamine-lesioned (6-OHDA) rat model
Dosage:10 and 30 mg/kg
Administration:PO or IP, once
Result:Showed significant potentiation of the effects of L-DOPA in this model.
TCS 46b (Compound 46b) is a potent, selective and orally active NMDA NR1A/2B receptor antagonist with an IC50 of 5.3 nM. TCS 46b is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体内研究：
TCS 46b (Compound 46b; 10 and 30 mg/kg; p.o. or i.p.; once) 在 6-OHDA 损伤大鼠中增强左旋多巴的作用。Animal Model:Sprague?Dawley rats, 6-hydroxydopamine-lesioned (6-OHDA) rat model
Dosage:10 and 30 mg/kg
Administration:PO or IP, once
Result:Showed significant potentiation of the effects of L-DOPA in this model.
产品资料
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