产品
编 号:F310474
分子式:C27H26O12
分子量:542.49
产品类型
结构图
CAS No: 30021-77-3
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产品详情
生物活性:
Cleistanthin B (Diphyllin O-glucoside) is an orally active arylnaphthalene lignan lactone glycoside. Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 μM. Cleistanthin B also exhibits antitumor, diuretic and antihypertensive effects in vivo.
体内研究:
Cleistanthin B (25-100 mg/kg; p.o. for 10 dys) has antitumor activity against EAC and DAL tumor mice but it is not effective against solid tumor.
体外研究:
Cleistanthin B exhibits anti-SARS-CoV-2 effects in Vero cells, with EC50 of 6.51 μM.Cleistanthin B shows no cytotoxic to Vero cells in concentrations up to 100 μM.