产品
编 号：F309960
分子式：C12H8O4
分子量：216.19
分子式：C12H8O4
分子量：216.19
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
500mg
280
In-stock
1g
336
In-stock
结构图
CAS No: 298-81-7
产品详情
生物活性：
Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
体内研究：
Methoxsalen（15mg/kg，腹腔注射，单剂量）增加尼古丁的 Cmax，延长血浆尼古丁半衰期（增加四倍），降低其清除率（减少六倍），并增加其 AUC[ 1]。Methoxsalen（15mg/kg，腹腔注射，单剂量）可增强口服尼古丁的药理作用（体温和镇痛）。Animal Model:Male adult ICR mice
Dosage:15 mg/kg
Administration:Intraperitoneal injection (i.p.), single dose
Result:Increased nicotine plasma levels were still above 10ng/ml at 6hr.Induced nicotine’s antinociceptive and hypothermic lasted close to 6 and 24 hr.
Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
体内研究：
Methoxsalen（15mg/kg，腹腔注射，单剂量）增加尼古丁的 Cmax，延长血浆尼古丁半衰期（增加四倍），降低其清除率（减少六倍），并增加其 AUC[ 1]。Methoxsalen（15mg/kg，腹腔注射，单剂量）可增强口服尼古丁的药理作用（体温和镇痛）。Animal Model:Male adult ICR mice
Dosage:15 mg/kg
Administration:Intraperitoneal injection (i.p.), single dose
Result:Increased nicotine plasma levels were still above 10ng/ml at 6hr.Induced nicotine’s antinociceptive and hypothermic lasted close to 6 and 24 hr.
产品资料
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