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编 号：F309844
分子式：C23H30NO3+
分子量：368.49
分子式：C23H30NO3+
分子量：368.49
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CAS No: 298-50-0
产品详情
生物活性：
Propantheline is an orally active mAChR antagonist. Propantheline can be used in the research of smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination.
体内研究：
Propantheline (oral administration, 10-300 mg/kg) decreased the fecal pellet count and the incidences diarrhea in restraint stress-induced bowel dysfunction rats.Animal Model:Restraint stress-induced bowel dysfunction models in rats
Dosage:10-300 mg/kg
Administration:Oral administration
Result:Decreased the fecal pellet count with ED50 values of 41 mg/kg.Dose-dependently decreased the incidences of diarrhea with ED50 values of 64 mg/kg.
体外研究：
Propantheline (10 μM-1 mM) decreases urinary bladder smooth muscle reactivity to Acetylcholine.
Propantheline is an orally active mAChR antagonist. Propantheline can be used in the research of smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination.
体内研究：
Propantheline (oral administration, 10-300 mg/kg) decreased the fecal pellet count and the incidences diarrhea in restraint stress-induced bowel dysfunction rats.Animal Model:Restraint stress-induced bowel dysfunction models in rats
Dosage:10-300 mg/kg
Administration:Oral administration
Result:Decreased the fecal pellet count with ED50 values of 41 mg/kg.Dose-dependently decreased the incidences of diarrhea with ED50 values of 64 mg/kg.
体外研究：
Propantheline (10 μM-1 mM) decreases urinary bladder smooth muscle reactivity to Acetylcholine.
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