产品
编 号：F307666
分子式：C18H28O5
分子量：324.41
分子式：C18H28O5
分子量：324.41
产品类型
规格
价格
是否有货
500μg
询价
询价
结构图
CAS No: 29066-42-0
产品详情
生物活性：
Hymeglusin, as a fungal β-lactone antibiotic, is a HMG-CoA synthase inhibitor (IC50 = 0.12 μM). Hymeglusin covalently modifies the active Cys129 residue of the enzyme.
体内研究：
At a dose of 25 mg/kg, hymeglusin inhibits cholesterol biosynthesis in rats by 45 %.
体外研究：
Hymeglusin inhibits dengue type 2 (DEN-2) New Guinea C (NGC) live virus replication in K562 cells. The therapeutic index (CC50/IC50) of Hymeglusin is 11. The EC50 of Hymeglusin in K562 cells is 4.5 μM.
Hymeglusin, as a fungal β-lactone antibiotic, is a HMG-CoA synthase inhibitor (IC50 = 0.12 μM). Hymeglusin covalently modifies the active Cys129 residue of the enzyme.
体内研究：
At a dose of 25 mg/kg, hymeglusin inhibits cholesterol biosynthesis in rats by 45 %.
体外研究：
Hymeglusin inhibits dengue type 2 (DEN-2) New Guinea C (NGC) live virus replication in K562 cells. The therapeutic index (CC50/IC50) of Hymeglusin is 11. The EC50 of Hymeglusin in K562 cells is 4.5 μM.
产品资料
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