产品
编 号:F307434
分子式:C18H24ClN3O7
分子量:429.85
产品类型
结构图
CAS No: 289893-26-1
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产品详情
生物活性:
Arimoclomol maleate (BRX-220) is a co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.
体内研究:
Arimoclomol maleate (BRX-220;20 mg/kg;口服;5 d) 对缩胆囊素八肽 (CCK) 诱导的急性胰腺炎具有保护作用。Animal Model:Male Wistar rats weighing 240 to 270 g
Dosage:20 mg/kg
Administration:Administered intragastrically, for 5 days
Result:Had a protective effect against CCK-induced acute pancreatitis.