产品
编 号：F307433
分子式：C14H20ClN3O3
分子量：313.78
分子式：C14H20ClN3O3
分子量：313.78
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CAS No: 289893-25-0
产品详情
生物活性：
Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.
体内研究：
Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect againstcholecystokinin-octapeptide (CCK)-induced acute pancreatitis.Animal Model:Male Wistar rats weighing 240 to 270 g
Dosage:20 mg/kg
Administration:Administered intragastrically, for 5 days
Result:Had a protective effect against CCK-induced acute pancreatitis.
Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP). Arimoclomol protects motor neurons by enhancing Hsp expression, thus directly affecting protein aggregation and clearance of misfolded assemblies via the proteasome-ubiquitin system.
体内研究：
Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect againstcholecystokinin-octapeptide (CCK)-induced acute pancreatitis.Animal Model:Male Wistar rats weighing 240 to 270 g
Dosage:20 mg/kg
Administration:Administered intragastrically, for 5 days
Result:Had a protective effect against CCK-induced acute pancreatitis.
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