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编 号:F306670
分子式:C19H18F2N4O
分子量:356.37
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10mM*1mL in DMSO
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5mg
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10mg
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100mg
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生物活性:
SB-408124 is a non-peptide OX1 receptor antagonist with Kis of 57 nM and 27 nM in whole cell and membrane, respectively. SB-408124 exhibits 50-fold selectivity over OX2 receptor.

体内研究:
SB-408124 (30 μg/10 μl; i.c.v.; male Wistar rats) decreases Orexin-A induced water intake in Wistar rats.
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