产品
编 号:F306317
分子式:C17H22N2O5S2
分子量:398.5
产品类型
结构图
CAS No: 287403-39-8
联系客服
产品详情
生物活性:
TMI-1 is a potent inhibitor of disintegrin metalloenzyme 17 (ADAM17) and other MMPs. TMI-1 inhibits LPS-induced TNF-α secretion in human primary monocytes, and human whole blood. TMI-1 selectively induces caspase-dependent apoptosis in triple negative (TN) and ERBB2-overexpressing breast tumor cell lines.