产品
编 号:F305977
分子式:C65H117N11O14
分子量:1276.69
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1mg
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5mg
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10mg
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生物活性:
Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.

体外研究:
Cyclosporin A-Derivative 1 is a non-immunosuppressive Cyclosporin A derivative. The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues). Cyclosporin A-Derivative 1 is a linear peptide intermediate.
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