产品
编 号:F305881
分子式:C12H10N2O5
分子量:262.22
产品类型
结构图
CAS No: 28657-80-9
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产品详情
生物活性:
Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis.
体内研究:
Cinoxacin (Oral administration, 1.7 g/kg, treated at 1 and 5 h postinfection) is effective in experimental bacterial infections in mice, with ED50 values ranging from 8.1 to 58.6 mg/kg.Animal Model:Indicated bacterial infected mice model
Dosage:1.7 g/kg, treated at 1 and 5 h postinfection
Administration:Oral administration
Result:Displayed antibacterial activity with ED50 values ranging from 8.1 to 58.6 mg/kg.
体外研究:
Cinoxacin (0-200μg/mL approximately, 3-24 h) inhibits many gram-negative aerobic bacteria with MIC values ranging from 4 to 64 μg/mL.