产品
编 号:F305863
分子式:C20H30O5
分子量:350.45
产品类型
结构图
CAS No: 28649-60-7
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产品详情
生物活性:
Epoxylathyrol, an epoxylathyrane derivative isolated from the Euphorbia boetica, is a P-glycoprotein (P-gp) inhibitor. Epoxylathyrol is a P-gp-mediated multidrug resistance (MDR) reverser.
体外研究:
Epoxylathyrol has no significant antiproliferative activity in EPG85-257P (parental; IC50>100 uM), EPG85-257RNOV (multidrug resistance [MDR] phenotype; IC50>100 uM), and EPG85-257RDB (multidrug resistance [MDR] phenotype; IC50=70.53 uM).