产品
编 号:F304665
分子式:C8H20NO6P
分子量:257.22
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10mM*1mL in DMSO
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询价
500mg
320
In-stock
1g
400
In-stock
5g
616
In-stock
10g
792
In-stock
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生物活性:
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia.

体内研究:
癫痫发作后用 sn-Glycero-3-phosphocholine (Choline Alfoscerate) (250 mg/kg;im;每日一次,持续 3 周) 处理可改善癫痫发作引起的认知障碍。 sn-Glycero-3-phosphocholine (Choline Alfoscerate) 增加大鼠海马中乙酰胆碱的释放,促进实验动物的学习和记忆,改善大脑转导机制并减少大鼠大脑中涉及学习和记忆的区域发生的年龄依赖性结构变化。Animal Model:Sprague-Dawley male rats
Dosage:250 mg/kg
Administration:Intramuscular injection; starting at 3 weeks after seizure and continuing daily for 3 weeks
Result:Improve seizure-induced cognitive impairment.
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