产品
编 号:F302838
分子式:C6H6O7
分子量:190.11
产品类型
结构图
CAS No: 27750-13-6
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产品详情
生物活性:
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis.
体内研究:
(-)-Hydroxycitric acid lactone (1000-3000mg/kg; fed for a period of 4 weeks) significantly decreases body weight at 2000 and 3000 mg/kg in chicken.Animal Model:1-day-old male broiler chickens
Dosage:1000, 2000, 3000 mg/kg
Administration:Fed for a period of 4 weeks
Result:Body weight and average daily gain (ADG) in the 2000 mg/kg and 3000 mg/kg were significantly lower.