产品
编 号：F035313
分子式：C23H38N2O3
分子量：390.56
分子式：C23H38N2O3
分子量：390.56
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CAS No: 109760-77-2
产品详情
生物活性：
D,L-erythro-PDMP is an erythro isomer of PDMP. D,L-erythro-PDMP causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase.
体外研究：
D,L-erythro-PDMP (0, 12, 25, 50 μM; 0, 4, 7, 10 days) shows an inhibitory effect on cell growth of rabbit skin fibroblasts.D,L-erythro PDMP (50 μM; 3 days) has cytotoxic of rabbit skin fibroblasts on cell morphology.D,L-erythro-PDMP (40 μM; 24 h; MDCK cells) induces a marked increase in glucosyltransferase specific activity: 14.6 nmol/h per mg protein.D,L-erythro-PDMP (40 μM; 6 h) protects the cells against loss of synthase in cells exposed to cycloheximide.
D,L-erythro-PDMP is an erythro isomer of PDMP. D,L-erythro-PDMP causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase.
体外研究：
D,L-erythro-PDMP (0, 12, 25, 50 μM; 0, 4, 7, 10 days) shows an inhibitory effect on cell growth of rabbit skin fibroblasts.D,L-erythro PDMP (50 μM; 3 days) has cytotoxic of rabbit skin fibroblasts on cell morphology.D,L-erythro-PDMP (40 μM; 24 h; MDCK cells) induces a marked increase in glucosyltransferase specific activity: 14.6 nmol/h per mg protein.D,L-erythro-PDMP (40 μM; 6 h) protects the cells against loss of synthase in cells exposed to cycloheximide.
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