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编 号：F035026
分子式：C22H31N3O5S
分子量：449.56
分子式：C22H31N3O5S
分子量：449.56
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CAS No: 109683-61-6
产品详情
生物活性：
Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities.
体内研究：
Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. Utibapril (2 μg/kg/day) significantly inhibits vascular ACE activity, and Utibapril (250 μg/kg/day) results in a significant inhibition of plasma ACE. Furthermore, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited after treatment with the higher doses of utibapril. FPL 63547 is rapidly and extensively excreted as the diacid in the bile but appeared in the urine in negligible amounts.
Utibapril is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activities.
体内研究：
Utibapril significantly inhibits plasma, renal, and vascular ACE but not ventricular ACE activity. Utibapril (2 μg/kg/day) significantly inhibits vascular ACE activity, and Utibapril (250 μg/kg/day) results in a significant inhibition of plasma ACE. Furthermore, angiotensin I-induced decreases in coronary flow in the isolated heart are significantly inhibited after treatment with the higher doses of utibapril. FPL 63547 is rapidly and extensively excreted as the diacid in the bile but appeared in the urine in negligible amounts.
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