产品
编 号:F301424
分子式:C3H6ClNO2
分子量:123.54
产品类型
结构图
CAS No: 2731-73-9
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产品详情
生物活性:
β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.
体外研究:
β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B.