产品
编 号：F300932
分子式：C14H13N8NaO4S3
分子量：476.49
分子式：C14H13N8NaO4S3
分子量：476.49
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
480
In-stock
500mg
1440
In-stock
结构图
CAS No: 27164-46-1
产品详情
生物活性：
Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
体内研究：
Cefazolin sodium (Subcutaneous injection; 300-500 mg/kg; once daily; 5 d) treatment improves learning and memory in mice after surgery.Animal Model:6- to 8-week-old male CD-1 mice underwent clinical exploratory laparotomy
Dosage:300-500 mg/kg
Administration:Subcutaneous injection; 300-500 mg/kg; once daily; 5 days
Result:Attenuated learning and memory dysfunction induced by the surgery.
体外研究：
Cefazolin sodium (0-300 μg/ml; 6 or 24 h) has a direct anti-inflammatory effect on C8-B4 cells stimulated by lipopolysaccharide.Cefazolin sodium (0-400 μM; 72 h) treatment inhibits IL-2, IL-4 and IL-15-induced cell proliferation.Cefazolin sodium (0-400 μM; 30 min) treatment inhibits IL-2, IL-4, IL-15 and IL-21-stimulated JAK3 phosphorylation.
Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
体内研究：
Cefazolin sodium (Subcutaneous injection; 300-500 mg/kg; once daily; 5 d) treatment improves learning and memory in mice after surgery.Animal Model:6- to 8-week-old male CD-1 mice underwent clinical exploratory laparotomy
Dosage:300-500 mg/kg
Administration:Subcutaneous injection; 300-500 mg/kg; once daily; 5 days
Result:Attenuated learning and memory dysfunction induced by the surgery.
体外研究：
Cefazolin sodium (0-300 μg/ml; 6 or 24 h) has a direct anti-inflammatory effect on C8-B4 cells stimulated by lipopolysaccharide.Cefazolin sodium (0-400 μM; 72 h) treatment inhibits IL-2, IL-4 and IL-15-induced cell proliferation.Cefazolin sodium (0-400 μM; 30 min) treatment inhibits IL-2, IL-4, IL-15 and IL-21-stimulated JAK3 phosphorylation.
产品资料
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