产品
编 号：F299733
分子式：C13H24N4O3S
分子量：316.42
分子式：C13H24N4O3S
分子量：316.42
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CAS No: 26839-75-8
产品详情
生物活性：
Timolol is a β-blocker available for both topical and systemic administration. Topical Timolol is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension. Timolol can also be used for the research of infantile hemangiomas, hypertension, myocardial infarction, migraine prophylaxis, and atrial fibrillation.Timolol also has cardioprotective effect.
体内研究：
Timolol has a cardioprotective effect via inhibition of ERS response in diabetic rats.Animal Model:Experimental diabetes model: 3-month old male Wistar rats.
Dosage:5 mg/kg
Administration:Timolol (5 mg/kg daily for 12-week)
Result:Showed cardioprotective effect.
体外研究：
Timolol can significantly prevent the increased lipid peroxidation level of the heart from diabetic rats. Timolol can induce a well-balanced ratio between oxidative stress and antioxidant defense system in the diabetic animals, can have an important cardioprotection against diabetes-induced ERS and associated apoptotic effects.
Timolol is a β-blocker available for both topical and systemic administration. Topical Timolol is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension. Timolol can also be used for the research of infantile hemangiomas, hypertension, myocardial infarction, migraine prophylaxis, and atrial fibrillation.Timolol also has cardioprotective effect.
体内研究：
Timolol has a cardioprotective effect via inhibition of ERS response in diabetic rats.Animal Model:Experimental diabetes model: 3-month old male Wistar rats.
Dosage:5 mg/kg
Administration:Timolol (5 mg/kg daily for 12-week)
Result:Showed cardioprotective effect.
体外研究：
Timolol can significantly prevent the increased lipid peroxidation level of the heart from diabetic rats. Timolol can induce a well-balanced ratio between oxidative stress and antioxidant defense system in the diabetic animals, can have an important cardioprotection against diabetes-induced ERS and associated apoptotic effects.
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