产品
编 号:F295268
分子式:C9H18NO
分子量:156.25
产品类型
结构图
CAS No: 2564-83-2
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产品详情
生物活性:
Tempo is a nitric oxide radical and a selective scavenger of ROS in mitochondria. Tempo is also an organocatalyst that disproportionates superoxide and oxidizes primary alcohols to aldehydes in a catalytic cycle. Tempo has mutagenic and antioxidant effects and can induceDNA strand breaks. Tempo also exerts cytotoxic and mutagenic properties in mouse lymphoma cells.
体外研究:
Tempo (1-5 mM; 4 h) 在 L5178Y 细胞中可引起 DNA 损伤,发挥细胞毒性和遗传毒性。Tempo (1-5 mM; 4 h) 导致小鼠淋巴瘤细胞中的 DNA 断裂。