产品
编 号：F294403
分子式：C17H26O11
分子量：406.38
分子式：C17H26O11
分子量：406.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
693
In-stock
1mg
182
In-stock
5mg
630
In-stock
10mg
980
In-stock
25mg
2030
In-stock
结构图
CAS No: 25406-64-8
产品详情
生物活性：
Morroniside has neuroprotective effect by inhibiting neuron apoptosis and MMP2/9 expression.
体内研究：
Morroniside reduces the expression of MMP2 and MMP9 in an I/R injury model. Treatment with Morroniside significantly reduces I/R?associated neuron apoptosis in a dose dependent manner. The results demonstrate that active caspase?3 and Bax are significantly upregulated in the model group compared with the control group, while Bcl?2 is significantly downregulated. The expression of active caspase?3 and Bax is significantly downregulated by Morroniside treatment in a dose?dependent manner, while the expression of Bcl?2 is significantly upregulated. Morroniside has an ameliorative effect on diabetes-induced alterations such as oxidative stress, inflammation, and apoptosis in the liver of type 2 diabetic db/db mice.
Morroniside has neuroprotective effect by inhibiting neuron apoptosis and MMP2/9 expression.
体内研究：
Morroniside reduces the expression of MMP2 and MMP9 in an I/R injury model. Treatment with Morroniside significantly reduces I/R?associated neuron apoptosis in a dose dependent manner. The results demonstrate that active caspase?3 and Bax are significantly upregulated in the model group compared with the control group, while Bcl?2 is significantly downregulated. The expression of active caspase?3 and Bax is significantly downregulated by Morroniside treatment in a dose?dependent manner, while the expression of Bcl?2 is significantly upregulated. Morroniside has an ameliorative effect on diabetes-induced alterations such as oxidative stress, inflammation, and apoptosis in the liver of type 2 diabetic db/db mice.
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