产品
编 号:F292923
分子式:C26H32ClFO5
分子量:478.98
产品类型
结构图
CAS No: 25122-57-0
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生物活性:
Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin. Clobetasone butyrate can be used to relieve corticosteroid-responsive dermatoses, including atopic?dermatitis and psoriasis.
体内研究:
Clobetasone butyrate (application on the skin; 0.05%; 7 weeks) induces epidermal thinning in skin, Clobetasone butyrate 7 weeks causes much less epidermal thinning in the pig than flurandrenolone (0.05%) or fluocinolone acetonide (0.025%), both of which causes severe atrophy.Animal Model:Large white domestic pig
Dosage:0.5% application on the skin
Administration:7 weeks
Result:Caused moderate to slight atrophy.