产品
编 号:F033332
分子式:C20H20N2O
分子量:304.39
产品类型
结构图
CAS No: 1093070-16-6
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产品详情
生物活性:
GRL0617 is a selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro), with an IC50 of 0.6 μM and a Ki value of 0.49 μM. GRL0617 also inhibits SARS-CoV with an EC50 of 14.5 μM. GRL0617 can be used for the research of severe acute respiratory syndrome.
体外研究:
GRL0617 (0-50 μM;48 h) 在 SARS-CoV 感染的 Vero E6 细胞中表现出显著的抗病毒活性。