产品
编 号:F291622
分子式:C25H30F3N3O2
分子量:461.52
产品类型
结构图
CAS No: 2479465-67-1
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产品详情
生物活性:
EBOV/MARV-IN-1 is a potent inhibitor of Ebola virus (EBOV) and Marburg virus (MARV), with broad-spectrum activity (EC50=0.31, and 0.82 μM, respectively) and low cytotoxicity (SI>100) in HeLa cells.
体外研究:
EBOV/MARV-IN-1 (12.5 μM; 48 h) inhibits HIV/EBOV-GP (EC50=12 nM) and HIV/MARV-GP (EC50=180 nM) pseudotype virus in A549 cells containing a luciferase reporter gene, with low cytotoxicity (SI =2088).