产品
编 号：F289285
分子式：C15H18O2
分子量：230.3
分子式：C15H18O2
分子量：230.3
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 24268-41-5
产品详情
生物活性：
Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis.
体外研究：
Furanodienone (0-573.8?μM; 24? hours) exhibits IC50 values : 56.4?μM (RKO), 73.7?μM (sw480), 251.1?μM (HT-29), 412.5?μM (sw620) and 573.8?μM (LoVo) at 24 hours, while that in 48?h are 51.8?μM (RKO), 44.18?μM (sw480), 168.9?μM (HT-29), 314.2?μM (sw620) and 502.1?μM (LoVo), respectively.Furanodienone (0-150 μM; 24? hours) induces apoptosis and shows increase in caspase-9 and -3 activity has been observed in both cells, whereas a relative minor effect on that of caspase-8 in RKO and HT-29 cells.Furanodienone (0-150?μM; 24 ?hours) increases the apoptotic rates from 2.34±0.45% to 19.45±2.37% and 27.34±0.79%, in RKO cells at 75 and 150?μM. whereas 12.4±1.08 and 20.64±3.02% apoptosis at the concentration of 75 and 150?μM are observed in HT-29 cells compared with 2.89±0.26%.
Furanodienone is one of the major bioactive constituents derived from Rhizoma Curcumae. Furanodienone induced apoptosis.
体外研究：
Furanodienone (0-573.8?μM; 24? hours) exhibits IC50 values : 56.4?μM (RKO), 73.7?μM (sw480), 251.1?μM (HT-29), 412.5?μM (sw620) and 573.8?μM (LoVo) at 24 hours, while that in 48?h are 51.8?μM (RKO), 44.18?μM (sw480), 168.9?μM (HT-29), 314.2?μM (sw620) and 502.1?μM (LoVo), respectively.Furanodienone (0-150 μM; 24? hours) induces apoptosis and shows increase in caspase-9 and -3 activity has been observed in both cells, whereas a relative minor effect on that of caspase-8 in RKO and HT-29 cells.Furanodienone (0-150?μM; 24 ?hours) increases the apoptotic rates from 2.34±0.45% to 19.45±2.37% and 27.34±0.79%, in RKO cells at 75 and 150?μM. whereas 12.4±1.08 and 20.64±3.02% apoptosis at the concentration of 75 and 150?μM are observed in HT-29 cells compared with 2.89±0.26%.
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