产品
编 号：F288812
分子式：C15H22O10
分子量：362.33
纯 度：99.0%
分子式：C15H22O10
分子量：362.33
纯 度：99.0%
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
528
In-stock
5mg
300
In-stock
10mg
480
In-stock
50mg
1200
In-stock
结构图
CAS No: 2415-24-9
产品详情
生物活性：
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects.
体内研究：
Catalpol (25-100?mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.Animal Model:C57BL/6 mice treated with renal ischemia/reperfusion surgery
Dosage:25 mg/kg, 50 mg/kg and 100?mg/kg
Administration:Intraperitoneal injection; once
Result:Clearly reduced blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal IRI mice.
体外研究：
Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.
Catalpol (Catalpinoside), an iridoid glycoside found in Rehmannia glutinosa. Catalpol has neuroprotective, hypoglycemic, anti-inflammatory, anti-cancer, anti-spasmodic, anti-oxidant effects and anti-HBV effects.
体内研究：
Catalpol (25-100?mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.Animal Model:C57BL/6 mice treated with renal ischemia/reperfusion surgery
Dosage:25 mg/kg, 50 mg/kg and 100?mg/kg
Administration:Intraperitoneal injection; once
Result:Clearly reduced blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal IRI mice.
体外研究：
Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.
产品资料
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