产品
编 号:F286155
分子式:C25H20F7NO4S
分子量:563.48
产品类型
结构图
CAS No: 2349368-16-5
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产品详情
生物活性:
XY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC50 of 30 nM and a Kd of 380 nM.
体内研究:
XY101 exhibits significant antitumor activities during the treatment period with tumor growth inhibition and is well tolerated without obvious body weight loss.
体外研究:
XY101 potently inhibits cell growth, colony formation, and the expression of androgen receptor (AR), AR-V7 and prostate-specific antigen (PSA).