产品
编 号:F285595
分子式:C10H8ClN4NaO2S
分子量:306.7
产品类型
结构图
CAS No: 23307-72-4
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产品详情
生物活性:
Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
体内研究:
Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections.Animal Model:14 male broiler chickens (30-day-old)
Dosage:60 mg/kg
Administration:Intravenous injection or oral administration (Pharmacokinetic Analysis)
Result:Serum drug concentrations at 0.083, 0.50, 2, 6, 24 and 72h were determined to be 99.62, 83.50, 72.68, 58.43, 38.66 and 13.14 μg/mL, respectively, by intravenous injection. By oral administration were determined as 4.33, 7.95, 16.46, 22.88, 16.03 and 5.74 μg/mL, respectively.
体外研究:
The elimination of Sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Sulfaclozine is weakly adsorbed on the surface of TiO2 at pH 7 (Sulfaclozine sodium 相关抗体: