产品
编 号:F285311
分子式:C25H33NO8
分子量:400.49
产品类型
结构图
CAS No: 23210-58-4
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产品详情
生物活性:
Ifenprodil tartrate is a typical noncompetitive NMDA receptor antagonist. Ifenprodil tartrate exerts high affinity at NR1A/NR2B receptors (IC50=0.34 μM) over 400-fold than at NR1A/NR2A receptors (IC50=146 μM). Ifenprodil tartrate inhibits GIRK (Kir3), reduces inward currents through the basal GIRK activity. Ifenprodil tartrate has the potential to be a cerebral vasodilator.
体外研究:
G protein-activated inwardly rectifying K+ channels (GIRK).