产品
编 号:F285212
分子式:C23H28O11
分子量:480.46
产品类型
结构图
CAS No: 23180-57-6
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产品详情
生物活性:
Paeoniflorin is a heat shock protein-inducing compound and commonly exists in the plants of Paeoniaceae family, with various biological activities, including anticancer activity, anti-inflammatory activity, enhancing cognition and attenuating learning impairment, anti-oxidative stress, antiplatelet aggregation, expansion of blood vessels, and reducing blood viscosity.
体内研究:
Paeoniflorin (intradermal injection; 25 and 100mg/kg; once daily; 20 days) shows favorable effects on experimental arthritis.Animal Model:SD rats with collagen induced arthritis
Dosage:25 and 100mg/kg
Administration:Intradermal injection; 25 and 100mg/kg; once daily; 20 days
Result:Decreased arthritis score, relieved ankle and paw swelling, improved spleen istopathology, decreased the levels of IgA, IgM, IgG and anti-CII antibody.
体外研究:
Paeoniflorin (80 μg/mL; 4-24 h) treatment can induce Hsp40 and Hsp27 as well as Hsp70.