产品
编 号：F285166
分子式：C11H12O4
分子量：208.21
分子式：C11H12O4
分子量：208.21
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
400
In-stock
结构图
CAS No: 2316-26-9
产品详情
生物活性：
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effects.
体外研究：
3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 μM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells. 3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) inhibits the expression levels of Nox4 and p22phox in L-02 cells. 3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells.3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner.
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway. Anti-apoptotic effects.
体外研究：
3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 μM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells. 3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) inhibits the expression levels of Nox4 and p22phox in L-02 cells. 3,4-Dimethoxycinnamic acid (25, 50 and 100 μM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells.3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner.
产品资料
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