产品
编 号:F285073
分子式:C25H23ClF2N4O2
分子量:484.93
产品类型
结构图
CAS No: 2314467-60-0
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产品详情
生物活性:
TRPV4 agonist-1 is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay.
体外研究:
TRPV4 agonist-1 (Compound 36) exhibits significantly increased potency (ECmax: 20 nM in the SOX9 reporter assay). TRPV4 agonist-1 is inactive against TRPV1 channels.