产品
编 号：F284320
分子式：C17H23FN6O2
分子量：362.4
分子式：C17H23FN6O2
分子量：362.4
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 2305087-92-5
产品详情
生物活性：
PDE9-IN-1 is a potent, selective, and orally bioavailable phosphodiesterase-9A (PDE9A) Inhibitor with an IC50 of 8.7 nM.
体内研究：
PDE9-IN-1 (2.5 and 5.0 mg/kg; Oral administration; daily for 21 days) effectively recovers learning and memory function.Animal Model:Unilateral common carotid artery occlusion (UCCAO) mouse model
Dosage:2.5 and 5.0 mg/kg
Administration:Oral administration; daily for 21 days
Result:Significantly reduced the day 6 escape latency time and increased the frequency of platform area crossings, and recovered learning and memory function. High dose group possibly improved the escape latency time of mice.
体外研究：
PDE9-IN-1 is excellent selectivity across PDE families.
PDE9-IN-1 is a potent, selective, and orally bioavailable phosphodiesterase-9A (PDE9A) Inhibitor with an IC50 of 8.7 nM.
体内研究：
PDE9-IN-1 (2.5 and 5.0 mg/kg; Oral administration; daily for 21 days) effectively recovers learning and memory function.Animal Model:Unilateral common carotid artery occlusion (UCCAO) mouse model
Dosage:2.5 and 5.0 mg/kg
Administration:Oral administration; daily for 21 days
Result:Significantly reduced the day 6 escape latency time and increased the frequency of platform area crossings, and recovered learning and memory function. High dose group possibly improved the escape latency time of mice.
体外研究：
PDE9-IN-1 is excellent selectivity across PDE families.
产品资料
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