产品
编 号：F283121
分子式：C13H6Cl5NO3
分子量：401.46
分子式：C13H6Cl5NO3
分子量：401.46
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
100mg
480
In-stock
结构图
CAS No: 2277-92-1
产品详情
生物活性：
Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity.
体内研究：
Oxyclozanide (15 mg/kg (羊)，10 mg/kg (牛)；口服) 在羊和牛中显示出抗寄生虫的效果。Oxyclozanide (1500-5000 mg/kg；口服，一次) 在大鼠急性毒性试验中出现多种中毒症状。Animal Model:Healthy male and female Wistar rats (100-150 g)
Dosage:5000, 3690, 2730, 2025 and 1500 mg/kg
Administration:Oral administration; 5000, 3690, 2730, 2025 and 1500 mg/kg; once
Result:Induced toxic symptoms of pression, rough hair, inappetence and cyanotic lips, limbs and tail. Induced swelling spleen, bleeding spots in the liver and swelling stomachs at high-dose group.
体外研究：
Oxyclozanide 抑制甲氧西林敏感 S. pseudintermedius 分离株 MIC 值为 0.5-1 μg/mL。Oxyclozanide 抑制甲氧西林耐药 S. pseudintermedius 分离株 MIC 值为 0.5-2 μg/mL。Oxyclozanide 抑制甲氧西林耐药 S. aureus (MRSA) MIC 值为 1 μg/mL。
Oxyclozanide is an orally active salicylanilide anthelmintic agent that mainly acts by uncoupling oxidative phosphorylation in flukes. Oxyclozanide shows good anti-adenovirus, anti-biofilm, antifungal, and antibacterial activity.
体内研究：
Oxyclozanide (15 mg/kg (羊)，10 mg/kg (牛)；口服) 在羊和牛中显示出抗寄生虫的效果。Oxyclozanide (1500-5000 mg/kg；口服，一次) 在大鼠急性毒性试验中出现多种中毒症状。Animal Model:Healthy male and female Wistar rats (100-150 g)
Dosage:5000, 3690, 2730, 2025 and 1500 mg/kg
Administration:Oral administration; 5000, 3690, 2730, 2025 and 1500 mg/kg; once
Result:Induced toxic symptoms of pression, rough hair, inappetence and cyanotic lips, limbs and tail. Induced swelling spleen, bleeding spots in the liver and swelling stomachs at high-dose group.
体外研究：
Oxyclozanide 抑制甲氧西林敏感 S. pseudintermedius 分离株 MIC 值为 0.5-1 μg/mL。Oxyclozanide 抑制甲氧西林耐药 S. pseudintermedius 分离株 MIC 值为 0.5-2 μg/mL。Oxyclozanide 抑制甲氧西林耐药 S. aureus (MRSA) MIC 值为 1 μg/mL。
产品资料
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