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编 号:F282811
分子式:C30H31F3N6OS
分子量:580.67
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生物活性:
CHMFL-ABL-121 is a highly potent type II ABL kinase inhibitor with IC50s of 2 nM and 0.2 nM against purified inactive ABL wt and T315I kinase protein, respectively.

体外研究:
CHMFL-ABL-121 dose-dependently inhibits BCRABL's auto-phosphorylation at Y245 site in K562 (EC50CHMFL-ABL-121 相关抗体:
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