产品
编 号:F281963
分子式:C17H13Cl2FN4O
分子量:379.22
产品类型
结构图
CAS No: 2252247-80-4
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产品详情
生物活性:
SHIP2-IN-1 is a potent SHIP2 inhibitor, inhibits SHIP2 activity, with an IC50 of 2 μM. SHIP2-IN-1 blocks GSK3β activation by phosphorylation at the Ser9 residue. SHIP2-IN-1 is used in the research of Alzheimer’s disease.
体外研究:
SHIP2-IN-1 (Compound 43; 10 μM) significantly inhibits PI(3,4)P2 production in HT22 cells.