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编 号:F281963
分子式:C17H13Cl2FN4O
分子量:379.22
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
SHIP2-IN-1 is a potent SHIP2 inhibitor, inhibits SHIP2 activity, with an IC50 of 2 μM. SHIP2-IN-1 blocks GSK3β activation by phosphorylation at the Ser9 residue. SHIP2-IN-1 is used in the research of Alzheimer’s disease.

体外研究:
SHIP2-IN-1 (Compound 43; 10 μM) significantly inhibits PI(3,4)P2 production in HT22 cells.
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