产品
编 号:F279237
分子式:C34H30N2O6S
分子量:594.68
产品类型
结构图
CAS No: 22204-24-6
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产品详情
生物活性:
Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis.
体内研究:
Pyrantel pamoate (10 mg/kg; p.o.; single) reduces the worms in A. ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.Animal Model:Male Syrian Golden hamsters (3-week-old; A. ceylanicum-infected).
Dosage:10 mg/kg
Administration:Oral administration; single.
Result:Exhibited worm burden reduction and worm expulsion rates of 87.2% and 63.4%, respectively.
体外研究:
Pyrantel pamoate (10 nM-10 μM; 72 h) shows good anti-A. suum and (0-168.2 M; 72 h) anti-N. americanus activity.