产品
编 号:F279181
分子式:C29H29F3N2
分子量:462.55
产品类型
结构图
CAS No: 2219320-08-6
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产品详情
生物活性:
MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively. MSC1094308 inhibits the D2 ATPase activity by binding to a agentable hotspot of p97. MSC1094308 can be used in study of cancer.
体外研究:
MSC1094308 (10 μM;8 小时) 诱导多聚泛素积累,作为 HCT116 细胞降解抑制的生物标志物。