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编 号：F279084
分子式：C13H8O6
分子量：260.2
分子式：C13H8O6
分子量：260.2
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CAS No: 22172-15-2
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生物活性：
Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.
体外研究：
Norswertianin (12.5-50 μM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells.Norswertianin (40 μM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest.Norswertianin (40 μM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion.
Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy.
体外研究：
Norswertianin (12.5-50 μM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells.Norswertianin (40 μM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest.Norswertianin (40 μM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion.
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