产品
编 号：F278877
分子式：C11H16N5O7PS
分子量：393.31
分子式：C11H16N5O7PS
分子量：393.31
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
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1mg
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5mg
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10mg
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25mg
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结构图
CAS No: 22140-20-1
产品详情
生物活性：
2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation.
体外研究：
2-Methylthio-AMP (2-MeSAMP) inhibits agonist-mediated αIIbβ3 activation in platelets. 2-methylthio-AMP (50 μM; for 5 minutes) does not significantly inhibit thrombin, PAR1-AP, PAR4-AP, or ADP-mediated platelet Ca2+ mobilization. 2-methylthio-AMP fails to inhibit Ca2+ mobilization in P2Y12-deficient mouse platelets and does not raise cAMP or induce vasodilator-stimulated phosphoprotein phosphorylation in wild-type platelets.
2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation.
体外研究：
2-Methylthio-AMP (2-MeSAMP) inhibits agonist-mediated αIIbβ3 activation in platelets. 2-methylthio-AMP (50 μM; for 5 minutes) does not significantly inhibit thrombin, PAR1-AP, PAR4-AP, or ADP-mediated platelet Ca2+ mobilization. 2-methylthio-AMP fails to inhibit Ca2+ mobilization in P2Y12-deficient mouse platelets and does not raise cAMP or induce vasodilator-stimulated phosphoprotein phosphorylation in wild-type platelets.
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