产品
编 号:F278276
分子式:C30H32Cl3N3O4
分子量:604.95
产品类型
结构图
CAS No: 220847-86-9
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产品详情
生物活性:
Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. Valategrast has the potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment.
体外研究:
Valategrast contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS).