产品
编 号：F278022
产品类型
规格
价格
是否有货
100μg
询价
询价
结构图
CAS No: 220578-59-6
产品详情
生物活性：
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic drug Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML).
体外研究：
Gemtuzumab ozogamicin(1-250 ng/mL；72小时) 对 CD33 阳性细胞具有细胞毒性。Gemtuzumab ozogamicin 是一种 ADC。抗体与 CD33 结合并随后内化后，Calicheamicin 主要通过诱导 DNA 损伤和随后的细胞凋亡来介导对 CD33 阳性骨髓细胞的细胞毒性。
Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic drug Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML).
体外研究：
Gemtuzumab ozogamicin(1-250 ng/mL；72小时) 对 CD33 阳性细胞具有细胞毒性。Gemtuzumab ozogamicin 是一种 ADC。抗体与 CD33 结合并随后内化后，Calicheamicin 主要通过诱导 DNA 损伤和随后的细胞凋亡来介导对 CD33 阳性骨髓细胞的细胞毒性。
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