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编 号：F276590
分子式：C32H52O2
分子量：468.75
分子式：C32H52O2
分子量：468.75
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CAS No: 2189-80-2
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生物活性：
Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis.
体外研究：
Taraxerol acetate(10-150?μM; 24 or 48 hours)induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50 values of 34.2 and 28.4?μM, at 24 and 48 h, respectively.Taraxerol acetate(10, 50 and 150?μM; 24 hours)induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150?μM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1?cell cycle arrest with a corresponding decrease in the number of S-phase cells.
Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis.
体外研究：
Taraxerol acetate(10-150?μM; 24 or 48 hours)induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50 values of 34.2 and 28.4?μM, at 24 and 48 h, respectively.Taraxerol acetate(10, 50 and 150?μM; 24 hours)induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150?μM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1?cell cycle arrest with a corresponding decrease in the number of S-phase cells.
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