产品
编 号:F273698
分子式:C27H37FO6
分子量:476.58
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25mg
400
In-stock
50mg
640
In-stock
100mg
960
In-stock
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生物活性:
Betamethasone valerate (Betamethasone 17-valerate), the 17-valerate ester of Betamethasone, is a topical corticosteroid with anti-inflammatory activity. Betamethasone valerate is used in the treatment of recurrent aphthous stomatitis. Betamethasone valerate inhibits the binding of the radiolabeled glucocorticoid dexamethasone (3H dexamethasone) to human epidermis and mouse skin with IC50s of 5 and 6 nM, respectively.

体内研究:
Betamethasone valerate (10 mg; 5 minutes; applied to the irritated site with a micro spatula) ointment inhibits about 50% of the ear edema without thymus atrophy.Betamethasone-17-valerate ointment (50 mg) inhibits homologous passive cutaneous anaphylaxis.Animal Model:Female Sprague-Dawley rats weighing 60-70 g (croton oil edema experiment)
Dosage:10 mg
Administration:Applied to the irritated site with a micro spatula; 5 minutes
Result:Inhibited about 50% of the ear edema without thymus atrophy.
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