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编 号:F270180
分子式:C13H17Cl2N3O2S
分子量:350.26
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生物活性:
HA-100 dihydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 dihydrochloride also used as a ROCK inhibitor.

体外研究:
HA-100 dihydrochloride 是 ATP 竞争性的抑制 MLC 激酶和 PKC,Ki 值分别为 61 和 6.5 μM。
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